Thursday 30 May 2019

Scientists engineer unique 'glowing' protein

Biophysicists from the Moscow Institute of Physics and Technology have joined forces with colleagues from France and Germany to create a new fluorescent protein. Besides glowing when irradiated with ultraviolet and blue light, it is exceedingly small and stable under high temperatures. The authors of the paper, published in the journal Photochemical & Photobiological Sciences, believe the protein holds prospects for fluorescence microscopy. This technique is used in research on cancer, infectious diseases, and organ development, among other things.

* This article was originally published here

Body parts respond to day and night independently from brain, studies show

Can your liver sense when you're staring at a television screen or cellphone late at night? Apparently so, and when such activity is detected, the organ can throw your circadian rhythms out of whack, leaving you more susceptible to health problems.

* This article was originally published here

Scientists identify a novel strategy to fight viral infections and cancer in animal model

A potential therapeutic strategy to treat viral infection and boost immunity against cancer is reported in the May 30 online issue of the journal Cell.

* This article was originally published here

Laser technique could unlock use of tough material for next-generation electronics

In 2004, researchers discovered a super thin material that is at least a 100 times stronger than steel and the best known conductor of heat and electricity.

* This article was originally published here

Resistance to Fusarium head blight holding in Illinois, study says

Illinois wheat growers, take heart. A new University of Illinois study shows no evidence of a highly toxic Fusarium head blight (FHB) variant, known as NA2, in the wheat-growing region of the state. The study also reinforces the effectiveness of wheat resistance to the fungal disease.

* This article was originally published here

A new mechanism for accessing damaged DNA

UV light damages the DNA of skin cells, which can lead to skin cancer. But this process is counteracted by DNA repair machinery, acting as a molecular sunscreen. It has been unclear, however, how repair proteins work on DNA tightly packed in chromatin, where access to DNA damage is restricted by protein packaging. Using cryo electron microscopy, researchers from the Thomä group at the Friedrich Miescher Institute for Biomedical Research (FMI) have identified a new mechanism whereby repair proteins detect and bind to damaged DNA that is densely packed in nucleosomes.

* This article was originally published here

Researchers discover a new way to protect against high-dose radiation damage

Radiotherapy is one of the most effective ways to destroy cancer cells and shrink tumors. Around 50 percent of patients with tumors located in the gastrointestinal cavity (liver, pancreas, colon, prostate, etc) receive this type of treatment, which has increased cancer survival rates in recent decades. However, intensive radiation therapy not only damages tumor cells, but also healthy intestinal cells, leading to toxicity in 60 percent of treated patients. Whereas reversal of toxicity is observed after radiotherapy has concluded, 10 percent of treated patients develop gastrointestinal syndrome, a disease characterized by intestinal cell death, resulting in the destruction of the entire intestine and patient death.

* This article was originally published here